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Scholarly Communication

Genome responses of trypanosome infected cattle

Agaba, Morris; Hulme, H.; Rennie, C.; Mwakaya, J.; Ogugo, M.; Brass, A.; Archibald, A.; Brass, A. and Kemp, S.J. Genome responses of trypanosome infected cattle. In: International Symposium on Animal Genomics for Animal Health., 23-25 October 2007, OIE HQ, World Organisation for Animal Health, 12 Rue de Prony, Paris France. (Unpublished)

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The encounter between cattle and trypanosomes elicits changes in the activities of both genomes - that of the host and that of the parasite. These changes determine the fate of the host and parasite and the outcome of the encounter. Although the outcome in most cattle is a slow death following progressive anaemia and loss of body condition, in other cattle the outcome is more favourable; these cattle regain the initiative, suppress parasite growth, recover from the initial clinical signs, gain weight, and reproduce normally. Cattle exhibiting this latter outcome are said to be trypanotolerant. Below is a synopsis of the genome responses that set apart the trypanotolerant cattle from the susceptible cattle during experimental trypanosome infection.

Item Type:Conference or Workshop Item (Other)
Uncontrolled Keywords:GENE; Cattle; Trypanosoma; Trypanosoma congolense; Congolense; Animal; Responses; Response; Trypanosome
Subjects:Q Science > QH Natural history > QH301 Biology
Q Science > QH Natural history > QH426 Genetics
Departments, Research Centres and Related Units:Academic Faculties, Institutes and Research Centres > Faculty of Science > Department of Biological Sciences
ID Code:316
Deposited On:20 Apr 2010 14:55
Last Modified:21 May 2012 10:18

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