McRonald, Fiona E. and Fleisher, David R. (2005) Anticipatory nausea in cyclical vomiting. BMC Pediatrics, 5 . Article Number: 3. ISSN 1471-2431
Available under License Creative Commons Attribution.
Background: Cyclical Vomiting Syndrome (CVS) is characterised by discrete, unexplained episodes of intense nausea and vomiting, and mainly affects children and adolescents. Comprehending Cyclical Vomiting Syndrome requires awareness of the severity of nausea experienced by patients. As a subjective symptom, nausea is easily overlooked, yet is the most distressing symptom for patients and causes many behavioural changes during attacks. Case presentation: This first-hand account of one patient's experience of Cyclical Vomiting Syndrome shows how severe nausea contributed to the development of anticipatory nausea and vomiting (ANV), a conditioned response frequently observed in chemotherapy patients. This conditioning apparently worsened the course of the patient's disease. Anticipatory nausea and vomiting has not previously been recognised in Cyclical Vomiting Syndrome, however predictors of its occurrence in oncology patients indicate that it could complicate many cases. Conclusion: We suggest a model whereby untreated severe and prolonged nausea provokes anxiety about further cyclical vomiting attacks. This anxiety facilitates conditioning, thus increasing the range of triggers in a self-perpetuating manner. Effective management of the nausea-anxiety feedback loop can reduce the likelihood of anticipatory nausea and vomiting developing in other patients.
|Additional Information:||Published: 24 March 2005. 4 pages (page numbers not for citation purposes).|
|Uncontrolled Keywords:||Cyclical Vomiting Syndrome; Comprehending Cyclical Vomiting Syndrome|
|Subjects:||R Medicine > R Medicine (General)|
|Departments, Research Centres and Related Units:||Academic Faculties, Institutes and Research Centres > Faculty of Medicine > School of Dental Sciences|
|Publisher's Statement:||© 2005 McRonald and Fleisher; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.|
|Deposited On:||04 Jul 2008 16:45|
|Last Modified:||21 May 2012 09:55|
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